Projects within the SFB 766
| Project | Titel | Research area | Head of Project |
|---|---|---|---|
A. | Bacterial Cell Envelope: Synthesis, Structures and Functions | ||
| A02 | Control and Activity of the Streptomyces Spore Wall Synthesizing Complex (SSSC) | Microbiology, Biochemistry | Prof. Dr. Wolfgang Wohlleben, |
| A03 | Self-resistance mechanisms of actinomycetes producing antibiotics targeting peptidoglycan biosynthesis | Genetics and Biochemistry of Secondary- Metabolites- Syntheses | PD Dr. Efthimia Stegmann, IMIT - Microbiology/ Biotechnology |
| A06 | Excretion of cytoplasmic proteins (ECP) in Staphylococcus | Microbiology, Molecular biology, Physiology | Prof. Dr. Friedrich Götz, IMIT - Microbial Genetics |
| A07 | Bistable expression of secondary cell wall glycopolymer biosynthesis genes: underlying mechanism and impact on virulence | Microbiology, Infectious disease | Prof. Dr. Christiane Wolz, Dr. Christopher Weidenmaier, IMIT - Medical Microbiology and Hygiene |
| A08 | Phospholipid synthesis and translocation by bacterial UPF0104 proteins | Infection Biology, Molecular Biology, Biochemistry | Prof. Dr. Andreas Peschel, IMIT - Medical Microbiology and Hygiene |
| A11 | Structure and biogenesis of cell-cell junctions in multicellular cyanobacteria | Microbiology, Cell differentiation | Prof. Dr. K. Forchhammer, PD Dr. Iris Maldener, IMIT - Microbiology/ Organismic Interactions |
| A12 | Cell-wall associated enzyme inhibitors of MraY and SPase: Mode of action studies | Microbiology, Biological Chemistry | PD Dr. Bertolt Gust; Prof. Dr. Stephanie Grond, Pharmazeutische Biologie/ Organische Chemie |
| A13 | Elucidation of the unique conjugative DNA-translocation machinery of mycelial streptomycetes by biochemical analysis and real time imaging | Microbiology, Cell biology, Biochemistry | Dr. G. Muth IMIT - Microbiology/Biotechnology |
| A15 | Turnover and recycling of the peptidoglycan-teichoic acid complex of Gram-positive cell wall | Bacterial physiology, Cell wall catabolism | PD. Dr. Ch. Mayer, IMIT - Microbiology/Biotechnology |
| A16 | The role of Type I Secretion Systems (T1SS) in formation of the heterocyst specific cell wall | Microbiology, Cell differentiation | PD Dr. Iris Maldener, IMIT - Microbiology/ Organismic Interactions |
| A17 | Spatiotemporal organization of peptidoglycan synthesis and cell division | Microbiology, Cell envelope organization | Prof. Dr. Heike Brötz-Oesterhelt, IMIT - Microbial Bioactive Compounds |
B. | Host-Pathogen-Interactions | ||
| B01 | Biogenesis of autotransporter adhesins of enteropathogenic Gram-negative bacteria | Infection Biology, Microbial pathogenesis, Molecular Biology | Dr. Monika Schütz, IMIT - Medical Microbiology and Hygiene |
| B04 | Structure and evolution of protein fibers at the bacterial cell surface | Biochemistry Structural Biology, Bioinformatics | Prof. Dr. Andrei Lupas, |
| B07 | Bacterial effector-mediated interference with PGN-perception in plants | Inter-organismic Interactions of Plants, Microbiology | Dr. Andrea Gust. Center for Molecular Biology of Plants, Biochemistry of Plants |
| B08 | Transmembrane Signaling in Bacterial Adenylate Cyclases | Pharmaceutical Biochemistry | Prof. Dr. J. Schultz, Pharmaceutical Biochemiestry |
| B11 | Biogenesis of outer membrane proteins in evolutionary context | Microbiology, Biochemistry | Prof. Dr. D. Rapaport, IFIB - Biochemie |
| B16 | Mechanisms governing polar localization and assembly of the host cell targeting type VI secretion system | Bacterial cell physiology and virulence | Dr. Sandra Schwarz, IMIT - Medical Microbiology and Hygiene |
| B14 | Analysis of the assembly of bacterial type III secretion systems | Medical Microbiology, Biochemistry | Dr. Samuel Wagner, IMIT - Medical Microbiology and Hygiene |
| B15 | Analysis of adherence mechanisms to host cells promoting T3SS-mediated toxin injection | Host-pathogen-interactions | Prof. Dr. med. Ingo Birger Autenrieth, IMIT - Medical Microbiology and Hygiene Dr. Filipp Oesterhelt, IMIT - Microbial Bioactive Compounds |
C. | Central Functions | ||
| Z01 | Coordination/Administration | Prof. Dr. Wolfgang Wohlleben, IMIT - Microbiology/ Biotechnology | |
| Z02 | Structural Analysis of Cell Wall Protein Components | Protein Biochemistry,Structural Biology Protein/Proteome Analysis | Prof. Dr. T. Stehle, IFIB - Biochemie Prof. Dr. B. Macek, Proteom Centrum Tübingen |