Uni-Tübingen

Subproject A07: Specificity of proteasome regulation by tail-anchored transcription factors

Principal Investigator:

Dr. Suayb Üstün
Universität Tübingen
ZMBP General Genetics
Auf der Morgenstelle 32
72076 Tübingen
+49 7071 29 73230
suayib.uestuenspam prevention@zmbp.uni-tuebingen.de

 

Summary:

The proteasome is involved in plant defence and is therefore exploited by pathogens. We have shown that the transcription factors NAC53/78 (i) regulate proteotoxic stress during bacterial infection, are essential for plant defence, and are degraded by the proteasome. We aim to elucidate (i) which other target genes are regulated by NACs, (ii) by which factors NACs are posttranslationally regulated, (iii) how subcellular sorting of NACs functions, and (iv) how NACs specifically modulate target genes. This should decipher how NACs integrate different signals to balance the trade-off between proteasome regulation and defence.

 

 

Privacy settings

Our website uses cookies. Some of them are mandatory, while others allow us to improve your user experience on our website. The settings you have made can be edited at any time.

or

Essential

in2code

Videos

in2code
YouTube
Google