Sub-project C01: Regulation of microRNA biogenesis and activity
Principle Investigator
Prof. Dr. Detlef Weigel
Max-Planck-Institut für Entwicklungsbiologie
Abteilung Molekularbiologie
Spemannstrasse 35 72076 Tübingen
Tel 07071 - 601 1411
Fax 07071 - 601 1412
Summary
TP C01 investigates factors that regulate the biogenesis and activity of either a subset of miRNAs or of all miRNAs in response to endogenous or environmental stimuli. Specific emphasis is placed on a comparison of the spectrum of longer RNAs that are bound by different miRNA biogenesis proteins. The hypothesis to be tested is that distinct spectra of bound RNAs are responsible for the differences in the effects of these factors on adaptation to the environment and plant development.