Sub-project B05: H2O2 perception and signaling: the role of AHK5
Principle Investigator
Prof. Dr. Klaus Harter
Universität Tübingen
ZMBP, Pflanzenphysiologie
Auf der Morgenstelle 1,
72076 Tübingen
Tel 07071 - 29 72605
Fax 07071 - 29 3287
klaus.harter@zmbp.uni-tuebingen.de
Universität Tübingen
IFIB, Strukturbiologie
Hoppe-Seyler-Str. 4, 72076 Tübingen
Tel 07071 - 29 73043
FAX 07071 - 29 5565
Summary
Histidine kinases (AHKs) play an important role in the integration of multiple endogenous and environmental signals in Arabidopsis. In project B05 we would like to analyze the atomic structure of the histidine kinase 5 (AHK5) and the function of AHK5 in the perception and signaling of H2O2 in the context of environmentally modified root growth and development. In addition we would like to study, how H2O2-dependent signals are integrated by AHK5-dependent processes with other signaling cascades and how this can result in specific cellular and physiological outputs.